Attachment but not penetration of bovine herpesvirus 1 is necessary to induce apoptosis in target cells.

نویسندگان

  • E Hanon
  • G Meyer
  • A Vanderplasschen
  • C Dessy-Doizé
  • E Thiry
  • P P Pastoret
چکیده

Bovine herpesvirus 1 (BHV-1) induces apoptotic cell death in bovine peripheral blood mononuclear cells and B-lymphoma cells. Using a BHV-1 glycoprotein H null mutant, we have demonstrated that although penetration of BHV-1 is not required, attachment of BHV-1 viral particles is essential for the induction of apoptosis.

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عنوان ژورنال:
  • Journal of virology

دوره 72 9  شماره 

صفحات  -

تاریخ انتشار 1998